Cell and Gene Therapy Unit (UTCG)

Discover the « Cell and Gene Therapy Unit » of the Nantes University Hospital, a hospital unit dedicated to the bioproduction of Advanced Therapy Drugs (ATD) for nearly 30 years.

Our expertise dedicated to clinical research

Within the framework of academic or industrial partnerships, our mission is to adapt and to transfer innovative production processes developed by research units or start-ups, to a level of production compatible with clinical use. This activity is governed by an ISO 9001 quality management system that guarantees the quality and the safety of the products manufactured as well as the complete traceability of operations. The UTCG ensures the clinical-grade production of ATDs and the management of their quality control.

The UTCG objective is to provide innovative products for clinical care in fields such as oncology, autoimmunity or regenerative medicine.

Which cells? 

UTCG has expertise in cell engineering processes (selection, amplification, gene transformation) applied to a variety of cell types in many clinical applications:

• T cells, including tumor-infiltrating T cells (TILs) or modified T cells such as CAR T-cells
• Mesenchymal cells
• Monocytes
• Hematopoientic stem cells
• Skin cells

The UTCG includes: 

• 2 controlled atmosphere production areas of 330 m² including 6 cell culture rooms and dedicated to the production of cell therapy and ex vivo gene therapy products.
• 1 quality control laboratory
• 1 research and development laboratory